Acquired Sensorineural Hearing Loss (SNHL), due to aging, exposure to noise or other environmental factors impacts hundreds of millions of people. According to the recently updated World Health Organization estimates, 1 in 4 people worldwide will have some degree of hearing loss by 2050. The growing prevalence of hearing loss is driven in large part by the global increase in ageing populations.
Disabling hearing loss has far-reaching consequences on people’s lives. Currently, there are no pharmaceutical products that can treat SNHL.The treatment of SNHL is limited to the use of hearing aids or cochlear implants. These prostheses do not treat the underlying physiological cause of the hearing impairment. Hearing aids perform poorly when a larger number of hair cells has been lost and in noisy environments. Understanding of speech in noise remains the major unmet medical need in people with SNHL.